Treatment of central precocious puberty: comparison of urinary gonadotropin excretion and gonadotropin-releasing hormone (GnRH) stimulation tests in monitoring GnRH analog therapy.
نویسندگان
چکیده
منابع مشابه
the side effects of gonadotropin releasing hormone analog (diphereline) in treatment of idiopathic central precocious puberty
treatment of central precocious puberty (cpp) is the administration of gnrh analogs. metabolic syndrome comprised metabolic disturbances that confer increased risk of (cvd) diabetes mellitus (dm) and cardiovascular disease. this study is a longitudinal prospective study in pediatric endocrinology clinic. 30 non-obese children with idiopathic cpp were involved. total body weight, height, blood p...
متن کاملGonadotropin-releasing hormone (GnRH) stimulation test before and after GnRH analogue treatment in central precocious puberty; can GnRH test simplify adequately?
Methods We identified 72 girls diagnosed with central precocious puberty, and they were treated with GnRH analogue (GnRHa) to suppress pubertal progression from 1 January 2011 to 31 January 2012. GnRH stimulation tests were done before and 4 weeks after the third dose of the GnRH analogue. Information on clinical manifestations and laboratory data were obtained by reviewing medical records. All...
متن کاملLuteinizing Hormone Secretion during Gonadotropin-Releasing Hormone Stimulation Tests in Obese Girls with Central Precocious Puberty
OBJECTIVE Girls with precocious puberty have high luteinizing hormone (LH) levels and advanced bone age. Obese children enter puberty at earlier ages than do non-obese children. We analyzed the effects of obesity on LH secretion during gonadotropin-releasing hormone (GnRH) tests in girls with precocious puberty. METHODS A total of 981 subjects with idiopathic precocious puberty who had underg...
متن کاملThe side effects of gonadotropin releasing hormone analog (diphereline) in treatment of idiopathic central precocious puberty.
Treatment of central precocious puberty (CPP) is the administration of GnRH analogs. Metabolic syndrome comprised metabolic disturbances that confer increased risk of (CVD) diabetes mellitus (DM) and cardiovascular disease. This study is a longitudinal prospective study in pediatric endocrinology clinic. 30 non-obese children with idiopathic CPP were involved. Total body weight, height, blood p...
متن کاملTREATMENT OF PRECOCIOUS PUBERTY BY A LONG-ACTING GONADOTROPIN-RELEASING HORMONE ANALOGUE IN CHILDREN
The GnRH analogue has been shown to be effective in the treatment of precocious puberty when given as a daily subcutaneous injection. We studied the effectiveness of a long-acting GnRH analogue, Triptoreline, for the treatment of central precocity, by suppressing gonadotropin and estradiol secretion in three children with true precocious puberty. One month after single dose intramuscular i...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1996
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.81.4.8636332